Medical Researches
Possibly Effective
Based on 14 Researches
We examined the role of selenium in treating myocardial infarction (MI), a major cause of death worldwide that can lead to serious heart problems. The study focused on how this antioxidant works across different phases of a heart attack, where harmful reactive oxygen species (ROS) play a significant role in worsening the condition.
Our findings highlighted a new approach using selenium-embedded nanoparticles, which are specially designed to act as antioxidants at various stages of MI. This innovative method allows for selective ROS elimination when it's most needed, leading to impressive recovery outcomes for the heart.
Throughout the research, it became clear that these nanoparticles help protect vital functions in heart cells by reducing cell death, inflammation, and scar tissue, while also encouraging new blood vessel growth. Overall, this self-sustaining antioxidant strategy shows great potential, not just for treating heart attacks but also inspiring therapies for other ischemic conditions.
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Selenium nanoparticles aid heart recoveryMitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
Direct focus on heart attack treatment
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
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Selenium's potential in cardiac recoveryFacile fabrication of biocompatible injectable blended polymeric hydrogel with bioactive nanoformulation to improving cardiac tissue regeneration efficiency after myocardial infarction for nursing care potential applications.
High relevance to cardiac applications
We investigated how selenium, specifically in the form of selenium nanoparticles (Se NPs), can play a role in recovering from heart attacks. Our study focused on developing a unique hydrogel that combines Se NPs with a polymer base to improve cardiac repair after acute myocardial infarction (MI).
We explored the effects of the Se NPs on human heart cells and conducted experiments on mice models. The results were promising; the hearts of the treated mice showed a significant improvement with the left ventricular wall thickness increasing from a mere 235.6 micrometers to an impressive 390 micrometers.
Not only did these treatments help thicken the heart walls, but we also saw a remarkable reduction in scar thickness and infarct size when compared to control groups. This suggests that our selenium-infused hydrogel could be a valuable solution to promote heart healing post-MI, paving the way for potentially advanced treatments in the future.
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Gold nanocages help heart recoveryL-Arginine-Loaded Gold Nanocages Ameliorate Myocardial Ischemia/Reperfusion Injury by Promoting Nitric Oxide Production and Maintaining Mitochondrial Function.
Selenium incorporated in composite treatment
We explored the potential of a novel treatment involving L-arginine-loaded gold nanocages designed to help with heart attack recovery. This innovative approach aims to tackle the problem of myocardial ischemia/reperfusion injury, a condition that can cause additional damage to the heart after blood flow is restored post-heart attack.
The gold nanocages in this study were enhanced with selenium and targeted towards heart cells, allowing for better absorption and effectiveness. Our tests showed that this treatment reduced cell damage and improved cell health during oxygen and glucose deprivation, which is crucial during heart attacks.
Furthermore, we observed that this treatment can help maintain mitochondrial function, leading to better energy production in heart cells. By preventing harmful oxidative reactions, it helps preserve nitric oxide, a vital molecule that supports heart health.
Ultimately, the results indicated that this approach could improve overall heart function and reduce cell death in heart tissue. The findings are promising and suggest a new pathway for effective heart attack treatments while ensuring safe and biocompatible use in living organisms.
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Selenium treatment for heart attackInjectable selenium-containing polymeric hydrogel formulation for effective treatment of myocardial infarction.
Direct evaluation of selenium's impact
We explored an innovative approach to treating heart attacks, specifically looking at how selenium can make a difference. Our study focused on a special injectable hydrogel made from a combination of selenium, polypropylene glycol, and polyethylene glycol. The goal was to see if this formulation could help reduce inflammation and fibrosis after a myocardial infarction (heart attack).
We conducted our research on a mouse model of myocardial infarction, observing the effects of our selenium-containing hydrogel. The results were promising—our formulation demonstrated the ability to promote recovery in heart function. Through various tests, including enzyme-linked immunosorbent assays and tissue analysis, we confirmed that the gel effectively inhibits harmful inflammation and fibrosis that often occur after a heart attack.
Overall, this work highlights the potential of selenium as a beneficial component in therapies for heart attacks and possibly other inflammatory conditions. Our findings suggest that a selenium-infused polymeric hydrogel could be an effective strategy for improving heart health in the aftermath of a myocardial infarction.
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User Reviews
Selenium is crucial for protecting against certain cancers and cardiovascular diseases, including heart attack and stroke. It also strengthens the immune system and enhances memory. Studies suggest it may help reduce asthma symptoms. Combining selenium with iodine improves absorption. Stay healthy!
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Consuming selenium-rich foods significantly lowers cardiovascular disease risk. Studies indicate that an increase in selenium levels can reduce the chance of heart attacks and coronary heart disease. This supplement also helps manage inflammation, which can trigger heart conditions.
Selenium plays a vital role in the body, impacting various biochemical processes. It benefits the heart, immune system, reproductive organs, and thyroid. Its antioxidant properties help mitigate the negative effects of free radicals, particularly beneficial for individuals with harmful habits impacting heart health.
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Selenium is essential for health! I've been taking it for autoimmune thyroiditis as prescribed by my doctor. It strengthens my immunity and overall well-being. One capsule daily prepares me for any challenge. I trust NOW products, and this specific selenium supplement has been effective. It serves various functions including antioxidant action, support for the immune system, and heart health, which is vital given the risk of heart attack.
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I purchased this selenium for my family, starting with two weeks of loading before adding iodine. My mother-in-law noticed significant improvements in her heart condition and cognitive function. She even asks when she can start taking it again, as she appreciates its effects.